Achievements

Long-Acting Injection

  • Overview
    A depot, long-acting injection is a specially designed injectable formulation that allows gradual and sustained drug release over an extended period, improving clinical outcomes in patients with low medication adherence.
    Possessed Technologies
    Microsphere spray-drying technology
    Microsphere emulsion technology
    Nano/micro suspension technology
    In situ gel technology
    Development of dual-chamber syringe (DCS)
    Distinguishing Point
    Robust pipeline based on platform technology
    Global collaboration with partners (Zydus, USA)
    Possession of facilities and core technologies spanning from research to production
    Development of exclusive dual-chamber syringe (DCS) for enhanced administration convenience, equipped with automatic filling system

Microsphere Emulsion Technology

  • Overview
    Microsphere Emulsion Technology involves dissolving active ingredients and biodegradable polymers in a solvent to prepare O/W or W/O/W emulsions, followed by solvent evaporation, microspheres collection, and freeze-drying to produce controlled-release microspheres.
    Distinguishing Point
    Reduction of adverse reactions through controlled initial release
    Ion channel technology enabling stable drug release profiles over target periods
    Dose reduction by maximizing encapsulation efficiency
    Holder of microsphere manufacturing patents

Microsphere Spray drying Technology

  • Overview
    Microsphere Spray-Drying Technology produces sustained-release microspheres by dissolving active ingredients and biodegradable polymers in a solvent and spray-drying them using an ultrasonic nozzle.
    Possessed Technologies
    Capability to manufacture uniform-sized sustained-release microspheres
    Enhanced safety by eliminating the use of organic solvents in the manufacturing process
    Holder of microsphere manufacturing patents

Dual-Chamber Syringe (DCS) Development

  • Overview
    The Dual-Chamber Syringe (DCS) is a pre-filled spyringe equipped with two separate chambers-one for the active drug and the other for the diluent—allowing immediate mixing and administration right before injection.
    Possessed Technologies
    Development of exclusive dual-chamber syringe (DCS) for improved administration convenience, equipped with automatic filling system
    Holder of patents for the DCS device